Overview

Why use herbal ingredients to support healthy blood pressure?†*
It's the safe, natural way to care for your heart:†

Specific herbs have been studied and clinically-proven to help support heart and circulatory health.†

Why take BP Manager^™†?
Because this proprietary herbal blend features five powerful, clinically-studied ingredients:†

• Stevia leaf extract supports healthy blood pressure levels.†*
• Hawthorn extract balances sodium and fluid levels.†
• Olive leaf extract supports blood pressure health.†
• Dandelion leaf helps reduce fluid retention.†
• Lycopene supports arteries, circulation and heart health.†

See the results in 8-weeks:†

Recent studies showed positive results when consumers used BP Manager^™† daily over an 8-week period.†*

*Maintains healthy blood pressure levels already within normal range.

Directions

Technical Data

BP Manager:

• Scientifically-studied formula†¹
• Supports healthy blood pressure already within normal levels†
• Exclusive, proprietary ingredient blend
• Optimum benefits will be noted within 8 weeks†
  
  
  HOW DOES IT WORK?
  Blood pressure is defined as the flow of the blood from the heart, and the resistance that blood flow encounters in the arteries and vessels. Two values are used to determine blood pressure levels. Systolic pressure is measured during the contraction of the heart and ventricles. Diastole occurs between contractions when the heart rests and the heart cavities fill with blood. Diastolic pressure alternates rhythmically with systolic pressure.

  The ingredients in BP Manager individually have a long history of traditional use, and have been shown in modern clinical studies to have significant benefits for heart health.† This proprietary blend was recently utilized in a scientific study in which 100% of participants experienced significant support for retention of healthy blood pressure levels already within normal limits.†¹

  BP Manager contains clinically-studied ingredients that support healthy systolic and diastolic blood pressure already within normal limits.† Research on other nutrients for the support of healthy blood pressure levels typically have found significant benefits only for the retention of healthy systolic blood pressure levels already within normal limits.† Support for diastolic was less consistently noted—until now.†^1,2

  Dandelion (Taraxacum officinale) Leaf Extract: Dandelion leaves are rich in vitamin A, and include amounts of vitamin C, vitamin D, various B vitamins, magnesium, potassium, and zinc among other nutrients. Dandelion has a long history of traditional use associated helping reduce fluid retention in the body.†³ Flavonoids isolated found in dandelions may be responsible for its beneficial effects.†^3-6

  Lycopene: is a member of the carotenoid family, related to beta-carotene. Research shows that lycopene is associated with greater free-radical scavenging ability than any other carotenoid.†^7,8 Increased intake of lycopene has been associated with beneficial support of heart health in clinical studies, including a multi-center study.†^9,10

  Lycopene is also currently being studied for its association with immune system and prostate health.†^11-13

  Stevia (Stevia rebaudiana) leaf extract: the leaf of stevia is considered the beneficial part of the plant.† Extracts of stevia have been shown to support healthy vasodilation, arterial wall health and blood pressure already within normal limits.†^14-16

  Stevia may have other benefits that extend beyond support of healthy blood pressure. Clinical studies also associated stevia extract with support of healthy blood sugar already within normal limits in all participants.†^17,18

  Olive (Olea europaea) Leaf Extract: Olives and olive oil are major components of the Mediterranean diet. Olive leaf extract contains the beneficial compound oleuropein, which is associated with healthy vasodilation and arterial structure.†^19-21

  Hawthorn (Crataegus spp. oxycantha) extract: Hawthorn has been associated with support of the heart since ancient times. Modern research considers bioflavonoid complexes in hawthorn leaf and flower, including vitex-2-rhamnoside, responsible for the plant's beneficial effects.† Hawthorn extract is associated with healthy arterial blood flow, normal blood vessel dilation and healthy sodium balance already within normal limits.†^22-29

  Hawthorn also supports healthy cholesterol levels already within normal limits, possibly through antioxidant activity.†^30-33 Like stevia extract, hawthorn also shows potential benefits supporting normal blood sugar levels already within healthy limits.†³⁴

  The following chart listing the benefits of each:

  Ingredient	Benefit
  Dandelion Leaf Extract	Dandelion leaves are rich in vitamin A and other nutrients. Dandelion leaf has been traditionally associated with support of healthy fluid balance in the body already within normal limits†3,5 Dandelion also helps reduce fluid retention in the body.†3,6
  Lycopene	Lycopene is a member of the carotenoid family that shows great antioxidant activity†7-8 In clinical studies, lycopene was associated with support of cardiovascular health.†9,10 Lycopene is also currently being studied for its association with immune system and prostate health.†11
  Stevia Extract	Shows support of healthy blood pressure already within normal limits, and is associated with normal arterial wall thinkness and support of healthy blood vessel dilation†14-16 Clinical studies also associated stevia extract with support of healthy blood sugar levels already within normal limits in all participants†17,18
  Olive Leaf Extract	Olive leaf extract contains the beneficial compound oleuropein, which is assocaited with healthy vasorelaxation and arterial structure.†19-21
  Hawthorn Extract	Traditionally used to support heart health.† Hawthorn contains procyanidins, which are associated with its beneficial effects for supporting heart health.†22-23,25

  
  RECOMMENDATIONS
  One tablet three times daily with meals.
  PRECAUTIONS
  Monitor your blood pressure regularly. Consult your healthcare practitioner prior to use if your blood pressure is outside the normal range, if you are taking blood pressure lowering medication, or if you are pregnant or nursing.
  HOW IS IT SUPPLIED?
  
  • 02869;90 Tablets
  
  STORAGE RECOMMENDATIONS
  Store at controlled room temperature, 59° to 86°F (15°-30°C).
  REFERENCES
  
  1. A pilot-study of the effectiveness and safety of an herbal blend in pre-hypertensive subjects. 2004. Unpublished.
  2. Qidwai W, Qureshi R, Hasan SN, Azam SI. Effect of dietary garlic (Allium Sativum) on the blood pressure in humans--a pilot study. J Pak Med Assoc. 2000 Jun;50(6):204-7. PMID: 10979632
  3. Kotilla-Racz E, Racz G, Solomon A. The action of Taraxacum officinale extracts on the body weight and diuresis of laboratory animals. Planta Med. 1974 Nov;26(3):212-7.
  4. Williams CA, Goldstone F, Greenham J. Flavonoids, cinnamic acids and coumarins from the different tissues and medicinal preparations of Taraxacum officinale. Phytochemistry. 1996 May;42(1):121-7. PMID: 8728061
  5. Dandelion Herb. In: Herbal Medicine: Expanded Commission E Monographs. Blumenthal M, Goldberg A, Brinkmann J, eds. Integrative Medicine Communications. Newton, MA. 2000;79-80.
  6. Taraxacum officinale. Monograph. Altern Med Rev. 1999 Apr;4(2):112-4. PMID: 10231611
  7. Di Mascio P, Kaiser S, Sies H. Lycopene as the most efficient biological carotenoid singlet oxygen quencher. Arch Biochem Biophys. 1989 Nov 1;274(2):532-8. PMID: 2802626
  8. Gianetti J, Pedrinelli R, Petrucci R, Lazzerini G, De Caterina M, Bellomo G, De Caterina R. Inverse association between carotid intima-media thickness and the antioxidant lycopene in atherosclerosis. Am Heart J. 2002 Mar;143(3):467-74. PMID: 11868053
  9. Arab L, Steck S. Lycopene and cardiovascular disease. Am J Clin Nutr. 2000;71(suppl):1691S-5S.
  10. Kohlmeier L, Kark JD, Gomez-Gracia E, Martin BC, Steck SE, Kardinaal AF, Ringstad J, Thamm M, Masaev V, Riemersma R, Martin-Moreno JM, Huttunen JK, Kok FJ. Lycopene and myocardial infarction risk in the EURAMIC Study. Am J Epidemiol. 1997 Oct 15;146(8):618-26. PMID: 9345115
  11. Agarwal S, Rao AV. Tomato lycopene and its role in human health and chronic diseases. CMAJ. 2000;163(6):739-744.
  12. Gann P, Ma J, Giovannucci E, Willett W, Sacks FM, Henneckens CH, et al. Lower prostate cancer risk in men with elevated plasma lycopene levels: results of a prospective analysis. Cancer Res. 1999;59:1225-30.
  13. Clinton SK, Emenhiser C, Schwartz SJ, Bostwick DG, Williams AW, Moore BJ, Erdman JW Jr. cis-trans lycopene isomers, carotenoids, and retinol in the human prostate. Cancer Epidemiol Biomarkers Prev. 1996 Oct;5(10):823-33. PMID: 8896894
  14. Melis MS. A crude extract of Stevia rebaudiana increases the renal plasma flow of normal and hypertensive rats. Braz J Med Biol Res. 1996 May;29(5):669-75. PMID: 9033821
  15. Lee CN, Wong KL, Liu JC, Chen YJ, Cheng JT, Chan P. Inhibitory effect of stevioside on calcium influx to produce antihypertension. Planta Med. 2001 Dec;67(9):796-9. PMID: 11745013
  16. Hsu YH, Liu JC, Kao PF, Lee CN, Chen YJ, Hsieh MH, Chan P. Antihypertensive effect of stevioside in different strains of hypertensive rats. Zhonghua Yi Xue Za Zhi (Taipei). 2002 Jan;65(1):1-6. PMID: 11939668
  17. Jeppesen PB, Gregersen S, Rolfsen SE, Jepsen M, Colombo M, Agger A, Xiao J, Kruhoffer M, Orntoft T, Hermansen K. Antihyperglycemic and blood pressure-reducing effects of stevioside in the diabetic Goto-Kakizaki rat. Metabolism. 2003 Mar;52(3):372-8. PMID: 12647278
  18. Curi R, Alvarez M, Bazotte RB, Botion LM, Godoy JL, Bracht A. Effect of stevia rebaudiana on glucose tolerance in normal adult humans. Braz J Med Biol Res. 1986;19(6):771-4. PMID: 3651629.
  19. Carluccio MA, Siculella L, Ancora MA, Massaro M, Scoditti E, Storelli C, Visioli F, Distante A, De Caterina R. Olive oil and red wine antioxidant polyphenols inhibit endothelial activation: antiatherogenic properties of Mediterranean diet phytochemicals. Arterioscler Thromb Vasc Biol. 2003 Apr 1;23(4):622-9. Epub 2003 Feb 20. PMID: 12615669
  20. Massaro M, De Caterina R. Vasculoprotective effects of oleic acid: epidemiological background and direct vascular antiatherogenic properties. Nutr Metab Cardiovasc Dis. 2002 Feb;12(1):42-51. PMID: 12125230
  21. Tuck KL, Hayball PJ. Major phenolic compounds in olive oil: metabolism and health effects. J Nutr Biochem. 2002 Nov;13(11):636-644. PMID: 12550060
  22. Walker AF, Marakis G, Morris AP, Robinson PA. Promising hypotensive effect of hawthorn extract: a randomized double-blind pilot study of mild, essential hypertension. Phytother Res. 2002 Feb;16(1):48-54.
  23. Svedstrom U, Vuorela H, Kostiainen R, Tuominen J, Kokkonen J, Rauha JP, Laakso I, Hiltunen R. Isolation and identification of oligomeric procyanidins from Crataegus leaves and flowers. Phytochemistry. 2002 Aug;60(8):821-5. PMID: 12150807
  24. Kirakosyan A, Seymour E, Kaufman PB, Warber S, Bolling S, Chang SC. Antioxidant capacity of polyphenolic extracts from leaves of Crataegus laevigata and Crataegus monogyna (Hawthorn) subjected to drought and cold stress. J Agric Food Chem. 2003 Jul 2;51(14):3973-6. PMID: 12822932
  25. Kim SH, Kang KW, Kim KW, Kim ND. Procyanidins in crataegus extract evoke endothelium-dependent vasorelaxation in rat aorta. Life Sci. 2000;67(2):121-31. PMID: 10901280
  26. Lininger, SW Jr. Hawthorn. In: The Natural Pharmacy, 2nd ed. Prima Publishing, Roseville, Ca. 1999;433-34.
  27. Schussler M, Holzl J, Fricke U. Myocardial effects of flavonoids from Crataegus species. Arzneimittelforschung. 1995 Aug;45(8):842-5. PMID: 7575743
  28. Havsteen B. Flavonoids, a class of natural products of high pharmacological potency. Biochem Pharmacol. 1983 Apr 1;32(7):1141-8. PMID: 6342623
  29. Uchida S, Ikari N, Ohta H, Niwa M, Nonaka G, Nishioka I, Ozaki M. Inhibitory effects of condensed tannins on angiotensin converting enzyme. Jpn J Pharmacol. 1987 Feb;43(2):242-6. PMID: 3033368
  30. Shanthi S, Parasakthy K, Deepalakshmi PD, Devaraj SN. Hypolipidemic activity of tincture of Crataegus in rats. Indian J Biochem Biophys. 1994 Apr;31(2):143-6. PMID: 7927437
  31. Zhang Z, Ho WK, Huang Y, James AE, Lam LW, Chen ZY. Hawthorn fruit is hypolipidemic in rabbits fed a high cholesterol diet. J Nutr. 2002 Jan;132(1):5-10. PMID: 11773500
  32. Zhang Z, Chang Q, Zhu M, Huang Y, Ho WK, Chen Z. Characterization of antioxidants present in hawthorn fruits. J Nutr Biochem. 2001 Mar;12(3):144-152. PMID: 11257463
  33. Bahorun T, Trotin F, Pommery J, Vasseur J, Pinkas M. Antioxidant activities of Crataegus monogyna extracts. Planta Med. 1994 Aug;60(4):323-8. PMID: 7938266
  34. Jouad H, Lemhadri A, Maghrani M, Burcelin R, Eddouks M. Hawthorn evokes a potent anti-hyperglycemic capacity in streptozotocin-induced diabetic rats. Herb Pharmcother. 2003;3(2):19-29.
  
  
  
  
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Testimonials

“After taking BP Manager for just four days, My blood pressure dropped significantly, while remaining within already normal limits. This product is worth every penny. I’m a firm believer in natural medicines and herbs. Because, with the right stuff, you can significantly support your health.”

Donna

“I can’t believe it; my blood pressure is in the normal range…something that works. Thanx”

Jim

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